001) in roflumilast treated patients compared with the placebo group.
Side Effects of Differin
What is Differin
This medicine is a retinoid-like compound, used to treat acne. It may also be used to treat other conditions as determined by your doctor.
This medicine may come with a patient information leaflet. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. Before applying differin, wash the affected area with a mild soap and gently dry. Apply a thin film of medicine to the affected and surrounding area. Rub in gently.
Drug Class and Mechanism
Adapalene is main ingridient of Differin. Adapalene in small concentrations is a Order Differin moderator of cellular differentiation, keratinization, and inflammatory processes. The exact mode of action of adapalene is unknown. Adapalene is applied topically to the skin, and its absorption into the blood through this medium is very low. Only trace amounts of adapalene have been found in the plasma of chronically treated patients.
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule.
Store differin at room temperature, away from heat and light.
Do not get this medicine in your eyes or on the inside of your nose or mouth. For the first 2 to 3 weeks of treatment, your skin condition may appear to worsen. This is expected. Do not stop using the medicine during this time. Do not use other medicines on your skin without first discussing it with your doctor. While you are using this medicine, you may use cosmetics. After using cosmetics, thoroughly wash and dry the affected area before applying this medicine. This medicine may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen if you must be outside. Do not apply this medicine to sunburned skin.
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Roflumilast acts differently to bronchodilators as it acts on the underlying condition, not primarily impacting on everyday symptoms.